Ipamorelin, The First Selective Growth Hormone Secretagogue

Ipamorelin, The First Selective Growth Hormone Secretagogue

Account

The account section typically provides information about the author’s institutional affiliation and personal credentials that establish expertise in peptide research. In the context of Ipamorelin, a detailed account would outline the researcher’s background in endocrinology, experience with growth hormone secretagogues, and any relevant clinical trials they have overseen or participated in.

Save citation to file

Researchers often need to preserve bibliographic information for future reference. The “Save citation to file” function allows you to export a formatted citation—usually in formats such as EndNote XML, RIS, or BibTeX—directly from the database. This ensures that all necessary metadata (authors, title, journal, volume, pages, DOI) is captured accurately for inclusion in reference management software.

Email citation

The “Email citation” feature facilitates quick sharing of a paper’s bibliographic details with colleagues or collaborators via email. By clicking this option, the system generates a ready-to-send email that contains the citation information and often a link to the full text, streamlining collaboration and literature reviews across research teams.

Add to Collections

“Add to Collections” lets users group related articles into custom libraries within the database. For Ipamorelin studies, a researcher might create a collection titled “Growth Hormone Secretagogues” or “Peptide Therapeutics,” allowing for easy retrieval of all relevant papers when drafting reviews or grant proposals.

Add to My Bibliography

Adding an article to “My Bibliography” integrates it into the user’s personal bibliography file. This feature often supports multiple citation styles (APA, MLA, Chicago) and can be exported for use in manuscripts, ensuring consistency across documents.

Your saved search

A “saved search” retains query parameters so that you can automatically receive updates when new literature matches your criteria. For Ipamorelin research, a user could save a search that pulls any newly published work on peptide agonists of the growth hormone secretagogue receptor (GHS-R1a), receiving alerts whenever a relevant study appears.

Create a file for external citation management software

Many databases allow users to generate files compatible with external reference managers such as Zotero, Mendeley, or EndNote. This function exports citations in XML or RIS format, simplifying the import process and enabling seamless integration into your research workflow.

Your RSS Feed

The RSS feed feature offers a way to subscribe to updates on specific topics or authors. By subscribing to an RSS feed for Ipamorelin or GHS-R1a agonists, researchers receive real-time notifications of new publications, conference abstracts, or patent filings that meet their search criteria.

Full text links

Full-text links provide direct access to the complete article, whether hosted on the publisher’s site or available via institutional repositories. For Ipamorelin studies, these links may lead to peer-reviewed journal articles, preprints, or supplementary materials such as datasets and protocols.

Actions

The “Actions” menu typically contains options for managing your interaction with the record: downloading PDFs, requesting interlibrary loans, exporting citations, sharing via social media, or adding notes. These actions streamline workflow from discovery to dissemination.

Page navigation

Page navigation offers quick jumps between sections of a database entry—abstract, methods, results, references—allowing researchers to efficiently locate specific information without scrolling through the entire record.

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Ipamorelin, the first selective growth hormone secretagogue

Ipamorelin is a hexapeptide (pyrrolidone-alanine-glutamine-phenylalanine-proline-glycine) that selectively binds to the GHS-R1a receptor. Unlike ghrelin or other non-selective analogs, Ipamorelin’s high affinity and minimal off-target activity make it a valuable tool for studying growth hormone dynamics and potential therapeutic applications in conditions such as sarcopenia, cachexia, and osteoporosis.

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Affiliation

The primary affiliation for Ipamorelin research often involves academic institutions with strong endocrinology departments—such as the University of Oxford or the University of Michigan—and pharmaceutical companies engaged in peptide drug development. Collaborative projects frequently combine basic science laboratories with clinical pharmacology units to evaluate safety profiles, dose-response curves, and therapeutic efficacy.

Authors

Typical authorship for Ipamorelin papers includes senior investigators (principal investigators), postdoctoral researchers, graduate students, and industry scientists. Authorship order reflects contribution: the first author usually conducts most experiments; the last author is often the laboratory head or funding principal investigator who oversees the project’s design and interpretation.

Abstract

A concise abstract summarizes Ipamorelin’s pharmacodynamics, key findings from in vitro receptor assays, animal studies demonstrating increased circulating growth hormone levels, and early-phase clinical trial results. It highlights the peptide’s selectivity, minimal appetite stimulation, and potential for long-term safety compared to earlier secretagogues.

Similar articles

The database’s “Similar articles” feature pulls related literature based on shared keywords (e.g., GHS-R1a agonist, growth hormone release, peptide therapeutics). These references help situate Ipamorelin within the broader landscape of endocrine modulators and provide context for comparative efficacy studies.

Cited by

The “Cited by” count indicates how many subsequent publications reference the Ipamorelin paper. A high citation number reflects influence on later research, such as meta-analyses or new clinical trials investigating peptide secretagogues in diverse patient populations.

MeSH terms

Medical Subject Headings (MeSH) classify the article under categories like “Peptides,” “Growth Hormone,” “Secretagogues,” and “Receptor Agonists.” These controlled vocabulary tags enable precise indexing for systematic reviews and database searches across biomedical literature.

Substances

The substances section lists chemical identifiers for Ipamorelin, including its IUPAC name, CAS number (e.g., 145345–93-1), SMILES notation, and any known analogs or metabolites. This information supports chemoinformatic analyses and facilitates regulatory submissions.

Related information

Related information aggregates supplementary data: clinical trial registries (ClinicalTrials.gov IDs), patent filings, FDA approval status, and safety advisories. For Ipamorelin, this may include ongoing Phase II studies exploring dosing regimens in elderly populations.

LinkOut – more resources

LinkOut connects to external databases such as PubChem, DrugBank, or the Protein Data Bank (PDB) for 3D structures of the GHS-R1a receptor bound to Ipamorelin. These links provide deeper mechanistic insights and support computational modeling efforts.

Full Text Sources

Full text sources enumerate all available repositories hosting the article: publisher’s website, open-access archives like PubMed Central, or institutional repositories. Users can access PDFs directly from these links without subscription barriers.

Other Literature Sources

This section aggregates related literature from non-traditional outlets—conference proceedings, dissertations, and grey literature—that discuss Ipamorelin or its analogs. Including such sources enriches the evidence base for translational research.

Medical

Medical resources linked here may include clinical guidelines, systematic reviews, and practice statements that reference Ipamorelin’s therapeutic potential. They provide clinicians with actionable insights into dosage, safety monitoring, and patient selection criteria.

Research Materials

Research materials list reagents, kits, or protocols essential for replicating Ipamorelin studies: peptide synthesis services, receptor binding assay kits, ELISA kits for measuring growth hormone, and animal models (e.g., GH-deficient rodents). This information is critical for laboratories aiming to reproduce or extend the findings.

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